Generalised anxiety disorder doubles risk of cardiovascular events in people with stable coronary heart disease

Does generalised anxiety disorder (GAD) affect cardiovascular events associated with coronary heart disease (CHD)? Population: 1015 patients with stable coronary heart. Eligible patients had at least one of the following: history of myocardial infarction (MI), 50% stenosis in one or more coronary vessels (angiographic evidence), history of coronary revascularization, diagnosis of CHD or previous evidence of exercise-induced ischaemia (treadmill or nuclear testing). Setting: Medical centres and public health clinics in San Francisco, USA; September 2000 to December 2002. Prognostic factors: GAD according to Diagnostic Interview Schedule for DSM-IV criteria. Outcomes:\ud Cardiovascular events occurring between baseline and March 2009. Events included stroke, heart failure, MI, transient ischaemic attack or death. Heart failure was defined as hospitalisation for a clinical syndrome involving at least two of the following: orthopnoea, third heart sound, pulmonary rales, paroxysmal nocturnal dyspnoea, elevated jugular venous pressure, cardiomegaly or pulmonary oedema on chest radiography. Non-fatal MI was defined based on the presence of symptoms, electrocardiographic changes and cardiac enzymes using standard criteria

Universal Non-Landau, Self-Organized, Lattice Disordering Percolative Dopant Network Sub-Tc Phase Transitions in Ceramic Superconductors

Ceramic superconductors (cuprates, pnictides, ...) exhibit universal features in both Tcmax and in their planar lattice disordering measured by EXAFS, as reflected by three phase transitions. The two highest temperature transitions are known to be associated with formation of pseudogaps and superconductive gaps, with corresponding Landau order parameters, but no new gap is associated with the third transition below Tc. It is argued that the third transition is a dopant glass transition, which is remarkably similar to transitions previously observed in chalcogenide and oxide alloy network glasses (like window glass)